For nearly 20 years, I have been enrolled in The Sister Study, a longitudinal research effort conducted by the National Institute of Environmental Health Sciences. I and more than 53,000 other women across the United States and Puerto Rico who have had a sister with breast cancer have enrolled in this landmark research effort to find causes of breast cancer. Highlights of the research can be found here.

There’s nothing to say about Doctors Without Borders. The name covers it. Sure, the organization replicates at least some existing global inequities, including sexism and racism. But at least for now, it’s a major source of unbiased (?) humanitarian aid in areas of acute, howling human need. A few dollars should go its way.

GiveDirectly lets donors send money directly to the world’s poorest households. No donation is too small, and active programs include poverty relief, disaster relief, climate survival, and refugee aid. GiveDirectly believes that people living in poverty deserve the dignity to choose for themselves how best to improve their lives, which is why the organization provides cash. After decades of top-down interventions that have spent billions (or even trillions) of dollars on the poorly targeted provision of services, this approach marks a major step forward in the reduction of extreme poverty—as shown by an ever-growing body of rigorous research.